CREB-1(Phospho Thr100) Polyclonal Antibody, 20ul Cellular Function Assays Mutations in this gene are

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD

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This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers

CREB-1(Phospho Thr100) Polyclonal Antibody, 20ul Cellular Function Assays Mutations in this gene areThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.