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Rho H Polyclonal Antibody, 100ul Yeast Expression It is located in the

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Rho H Polyclonal Antibody, 100ul Yeast Expression It is located in theThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to

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Description

It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS

The encoded protein may play an antioxidant protective role in cells| and may contribute to the antiviral activity of CD8(+) T-cells

differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence

It exists as two isoenzymes

Rho H Polyclonal Antibody, 100ul Yeast Expression It is located in theThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to

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