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Ku-70 Polyclonal Antibody, 20ul[BT-AP04896] DNA Synthesis and facilitates the formation of

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Ku-70 Polyclonal Antibody, 20ul[BT-AP04896] DNA Synthesis and facilitates the formation ofThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

and facilitates the formation of a stable complex with the BCR-ABL oncoprotein

Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex

Alternative splicing results in multiple transcript variants encoding the same isoform

Several transcript variants are formed through the use of alternative translation initiation sites and promoters

Ku-70 Polyclonal Antibody, 20ul[BT-AP04896] DNA Synthesis and facilitates the formation ofThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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