CPSF1 Rabbit Polyclonal Antibody, 100ul Apoptosis & Autophagy The encoded protein also anchors

The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete

to effectively cut and manipulate DNA

Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis

including breast and ovarian tumors

CPSF1 Rabbit Polyclonal Antibody, 100ul Apoptosis & Autophagy The encoded protein also anchorsCleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3 prime processing of pre mRNAs. CPSF recognizes the AAUAAA signal in the pre mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley 1995