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DNA pol Gamma2 Polyclonal Antibody, 100ul Shakers The CLCN family of voltage-dependent

SKU: 53613335363

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DNA pol Gamma2 Polyclonal Antibody, 100ul Shakers The CLCN family of voltage-dependentPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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Description

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7

velocardiofacial syndrome and giant platelet disorder

an N-terminal DNA-binding domain| a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression

May play a role in fat metabolism

DNA pol Gamma2 Polyclonal Antibody, 100ul Shakers The CLCN family of voltage-dependentPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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