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Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases Chloride intracellular channel 4 (CLIC4)

SKU: 53608798349

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PLN111.00 PLN133.00

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Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases Chloride intracellular channel 4 (CLIC4)This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas including skin fragility woolly hair syndrome. Alternative splicing results in multiple transcript variants.

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Description

Chloride intracellular channel 4 (CLIC4) protein

tissue specificity:Expressed in lung and macrophages

The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region

An important paralog of this gene is HIST1H2BH

Desmoplakin(Phospho-Ser165/166) Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases Chloride intracellular channel 4 (CLIC4)This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas including skin fragility woolly hair syndrome. Alternative splicing results in multiple transcript variants.

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