WNK4 Polyclonal Antibody, 50ul Thermal Control Function: putative pheromone receptor

Function: putative pheromone receptor

Isoform 2 does not interact with CUL4A but still binds to RBX1

Alternate allele-specific splice variants

It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain

WNK4 Polyclonal Antibody, 50ul Thermal Control Function: putative pheromone receptorThis gene encodes a member of the WNK family of serine threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.