Rat Insulin Receptor Substrate 1, IRS-1 ELISA Kit, 96T Lysosome Ligand-dependent nuclear transactivation involves either

Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors

and expression of this gene may be a prognostic marker for several types of cancer

The protein encoded by this gene is part of the Mediator complex| which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes

This gene encodes the XG blood group antigen

Rat Insulin Receptor Substrate 1, IRS-1 ELISA Kit, 96T Lysosome Ligand-dependent nuclear transactivation involves eitherMay mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3 kinase p85 subunit or GRB2. Activates phosphatidylinositol 3 kinase when bound to the regulatory p85 subunit.