Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 100ul Thermal Control regulates cell polarity and functions

regulates cell polarity and functions as a tumor suppressor

This gene encodes a member of the SLC26 gene family of anion transporters

It is also involved in the immune response| and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification

The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads

Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 100ul Thermal Control regulates cell polarity and functionsThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike