M3K14 Polyclonal Antibody, 20ul Endonucleases & Exonucleases It is overexpressed in cervical

It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member

a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

and monoallelic expression from the maternal and paternal alleles in different tissues

although the functional consequences of these have not yet been established

M3K14 Polyclonal Antibody, 20ul Endonucleases & Exonucleases It is overexpressed in cervicalThis gene encodes mitogen activated protein kinase kinase kinase 14, which is a serine threonine protein kinase. This kinase binds to TRAF2 and stimulates NF kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF kappaB inducing signalling cascade common to receptors of the tumour necrosis nerve growth factor (TNF NGF) family and to the interleukin 1 type I receptor.