Ksr2 Polyclonal Antibody, 100ul Cell Proliferation This gene encodes a bifunctional

This gene encodes a bifunctional signal transduction molecule

Also expressed in Barrett's esophagus epithelium and in the proximal duodenum

Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons

The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction

Ksr2 Polyclonal Antibody, 100ul Cell Proliferation This gene encodes a bifunctionalLocation regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8 mediated signaling. Acts as a negative regulator of MAP3K3 mediated activation of ERK, JNK and NF kappa B pathways, inhibiting MAP3K3 mediated interleukin 8 production.