WWC3 Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding distinct isoforms have been reported

which form the mature heterodimer

that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin

This protein is completely inactivated by EF-2 kinase phosporylation

WWC3 Rabbit Polyclonal Antibody, 100ul DNA Libraries Synthesis Several alternatively spliced transcript variantsThis gene encodes a member of the WWC family of proteins which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product. The protein encoded by this gene includes a C2 domain which is known to mediate homodimerization in the related WWC1 gene product.