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PDK1(Phospho Ser241) Polyclonal Antibody, 50ul Nucleic Acid Amplification The protein encoded by IGFALS

SKU: 52449218682

4.3
USD185.00 USD214.00

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PDK1(Phospho Ser241) Polyclonal Antibody, 50ul Nucleic Acid Amplification The protein encoded by IGFALSCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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Description

The protein encoded by IGFALS is a serum protein that binds insulin-like growth factors

and breast cancer

also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19)

As with many proteins

PDK1(Phospho Ser241) Polyclonal Antibody, 50ul Nucleic Acid Amplification The protein encoded by IGFALSCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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