Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes Mutations in this gene have

Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2)

The protein encoded by this gene is highly similar to S

GPR37 is a member of the G protein-coupled receptor family

PTM:Phosphorylated upon DNA damage

Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes Mutations in this gene haveThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding