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ATP-citrate synthase Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene are

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ATP-citrate synthase Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene areATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients

Is also detected in several tumors types

A pseudogene corresponding to MRPL32 is found on chromosome Xp

are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles

ATP-citrate synthase Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Mutations in this gene areATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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