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MSH2 Monoclonal Antibody, 50ul Cellular Cultivation & Health Management Mitogen-activated protein kinase kinase kinase

SKU: 52146371038

4.1
USD185.00 USD209.00

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MSH2 Monoclonal Antibody, 50ul Cellular Cultivation & Health Management Mitogen-activated protein kinase kinase kinaseThis locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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Description

Mitogen-activated protein kinase kinase kinase 7 encoded by MAP3K7 is a member of the serine/threonine protein kinase family

Dynamin 1 like mediates mitochondrial and peroxisomal division

which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits

Ral (see MIM 179550)

MSH2 Monoclonal Antibody, 50ul Cellular Cultivation & Health Management Mitogen-activated protein kinase kinase kinaseThis locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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