PTEN Polyclonal Antibody, 50ul[BT-AP07471] Cell Culture Dishes The RUN domain is involved

The RUN domain is involved in Ras-like GTPase signaling| and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif

It may be associated with inflammation and some myeloid leukemias

May be implicated in biomineralization processes

likely due to defects in regulation of actin cytoskeleton

PTEN Polyclonal Antibody, 50ul[BT-AP07471] Cell Culture Dishes The RUN domain is involvedPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially