KCMB1 Polyclonal Antibody, 20ul Enzymes & Activity Assays A mutation in this gene

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

including membrane receptor signaling

NMBR encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B

Cofactor binding induces a conformation change

KCMB1 Polyclonal Antibody, 20ul Enzymes & Activity Assays A mutation in this geneMaxiK channels are large conductance, voltage and calcium sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.