p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis Mutations in this gene result

Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits

FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF)

This protein also interacts with the nuclear pore complex glycoprotein p62

p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis Mutations in this gene resultTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.