EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Transcripts for this gene undergo

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development

Three transcript variants encoding two different proteins have been found for this gene

Additional variants have been found but their full-length nature has not been determined

EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Transcripts for this gene undergoEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.