I-TAC Rabbit Polyclonal Antibody, 100ul Vessels CCDC45 (coiled-coil domain containing 45)

CCDC45 (coiled-coil domain containing 45) is a 821 amino acid protein encoded by a gene that maps to human chromosome 17q23

An important paralog of this gene is NDUFC2-KCTD14

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Might be involved in the regulation of intracellular calcium in tracheal epithelial cells

I-TAC Rabbit Polyclonal Antibody, 100ul Vessels CCDC45 (coiled-coil domain containing 45)disease: Expressed in a variety of skin disorders including allergic contact dermatitis lichen planus and mycosis fungoides. Chemotactic for interleukin activated T cells but not unstimulated T cells neutrophils or monocytes. Induces calcium release in activated T cells. Binds to CXCR3. May play an important role in CNS diseases which involve T cell recruitment. May play a role in skin immune responses. induction: By interferon gamma and interferon