InsP 3-kinase B Polyclonal Antibody, 50ul Cell Separation and Collection At least three alternatively spliced

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

T and their related proteins

The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related))

This gene localizes within the class III region of the MHC on the short arm of chromosome 6

InsP 3-kinase B Polyclonal Antibody, 50ul Cell Separation and Collection At least three alternatively splicedThe protein ITPKB encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5 trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium calmodulin and protein phosphorylation mechanisms control its activity.