IRS-1 Polyclonal Antibody, 100ul[BT-AP04642] DNA Oligo Synthesis The WD40 group is a

The WD40 group is a large family of proteins

The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities

The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers

It is now widely accepted that KSR1 functions as a scaffold that binds MEK1/2 and 14-3-3 protein constitutively and binds ERK1/2 in a Ras activation-dependent manner

IRS-1 Polyclonal Antibody, 100ul[BT-AP04642] DNA Oligo Synthesis The WD40 group is aIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.