NUAK2 Polyclonal Antibody, 20ul Oligo Pool The Ku p70/p86 dimer acts

The Ku p70/p86 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold

Pseudogenes of NFE2L3 are found on chromosomes 16

both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters

|subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds

NUAK2 Polyclonal Antibody, 20ul Oligo Pool The Ku p70/p86 dimer actsCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Thr 208 by STK11 in complex with STE20 related adapter alpha (STRAD alpha) pseudo kinase and CAB39.,Stress activated kinase involved in tolerance to glucose starvation. Induces cell cell detachment by increasing F actin conversion to G actin. Expression is induced by CD95 or TNF alpha, via NF kappa B. Protects cells