WFS1 Polyclonal Antibody, 100ul Custom RNA Oligos Mutations in this gene are

Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome

aggressive behavior in Alzheimer disease patients

First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB)

insects and mammalian cells

WFS1 Polyclonal Antibody, 100ul Custom RNA Oligos Mutations in this gene areThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.