SIKE1 Polyclonal Antibody, 50ul Plasmid Preparation Mammalian mitochondrial ribosomal protein L

Mammalian mitochondrial ribosomal protein L 40 (39S ribosomal protein L40 mitochondrial) is encoded by nuclear gene MRPL40 and help in protein synthesis within the mitochondrion

Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state

The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis

The encoded protein contains several laminin G| Kazal type serine protease inhibitor| and epidermal growth factor domains

SIKE1 Polyclonal Antibody, 50ul Plasmid Preparation Mammalian mitochondrial ribosomal protein LSIKE interacts with IKK epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus triggered interferon activation pathways (Huang et al., 2005