Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis Take precise risks and achieve

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There are two isoforms of PRPF38A that are produced as a result of alternative splicing events

Exhibits low fidelity and efficiency opposite a thymidine template

Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis Take precise risks and achieveThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.