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IGF-I Receptor beta(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging stimulating cell proliferation

SKU: 49742785147

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IGF-I Receptor beta(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging stimulating cell proliferationThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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Description

stimulating cell proliferation

Shd and Shf are thought to function as adaptor proteins

RCBTB1 maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies

suggesting an important link between basal transcription control and the cell cycle machinery

IGF-I Receptor beta(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 100ul Lentiviral Packaging stimulating cell proliferationThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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