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Rb(Phospho Ser811) Polyclonal Antibody, 20ul Micro Centrifuge Tubes ADAMTS family members share several

SKU: 49734363673

4.5
PLN97.20 PLN142.20

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Rb(Phospho Ser811) Polyclonal Antibody, 20ul Micro Centrifuge Tubes ADAMTS family members share severalThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

ADAMTS family members share several distinct protein modules

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A

This enzyme is the major liver enzyme and functions in liver drug clearance

Expressed at lower level in neural tissues and at the highest level in the adrenal gland

Rb(Phospho Ser811) Polyclonal Antibody, 20ul Micro Centrifuge Tubes ADAMTS family members share severalThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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