SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance The promoter of this gene

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

which may contribute to its ability to reduce the tumorigenic phenotype in cells

This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses

|PTM:S-nitrosylation of Cys-61 affects DNA binding

SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance The promoter of this geneThis gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis renal dysfunction and cholestasis 2). Alternative splicing results in multiple transcript variants.