MTU1 Rabbit Polyclonal Antibody, 100ul Gene Synthesis POLQ (Polymerase (DNA) Theta) is

POLQ (Polymerase (DNA) Theta) is a Protein Coding gene

GO annotations related to this gene include nucleotide binding and calmodulin binding

makes it less likely to obstruct the target protein’s structure or function and more suitable to use under denaturing conditions

The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity

MTU1 Rabbit Polyclonal Antibody, 100ul Gene Synthesis POLQ (Polymerase (DNA) Theta) isThis nuclear gene encodes a mitochondrial tRNA modifying enzyme. The encoded protein catalyzes the 2 thiolation of uridine on the wobble positions of tRNA(Lys) tRNA(Glu) and tRNA(Gln) resulting in the formation of 5 taurinomethyl 2 thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations.