Fhit Polyclonal Antibody, 100ul[BT-AP03231] Pathway and Network Analysis Mutations in DES are associated

Mutations in DES are associated with desmin-related myopathy

It is crucial for cell viability under non-optimal growth conditions when HSP 90 levels are limiting

which regulates its rapid exchange between the plasma membrane and the Golgi apparatus

The products encoded by these genes function in signal transduction pathways

Fhit Polyclonal Antibody, 100ul[BT-AP03231] Pathway and Network Analysis Mutations in DES are associatedFHIT, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced