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Rat Kynurenine 3-monooxygenase, KMO ELISA Kit, 96T Protein Post-translational Modification Seems to be involved in

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Rat Kynurenine 3-monooxygenase, KMO ELISA Kit, 96T Protein Post-translational Modification Seems to be involved inCatalyzes the hydroxylation of L kynurenine (L Kyn) to form 3 hydroxy L kynurenine (L 3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal

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Description

Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity)

This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions

This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides

This protein can interact with integrin-linked kinase (ILK/ILK1)

Rat Kynurenine 3-monooxygenase, KMO ELISA Kit, 96T Protein Post-translational Modification Seems to be involved inCatalyzes the hydroxylation of L kynurenine (L Kyn) to form 3 hydroxy L kynurenine (L 3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal

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