NU205 Polyclonal Antibody, 50ul Insect Expression The crooked neck (crn) gene

The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing

is a 513 amino acid protein that exists as three alternatively spliced isoforms

The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras

Mutations in this gene are associated with pyridoxine-dependent epilepsy

NU205 Polyclonal Antibody, 50ul Insect Expression The crooked neck (crn) geneThis gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with steroid resistant nephrotic syndrome.