E2F-5 Polyclonal Antibody, 100ul Pathway and Network Analysis Activated by phosphorylation at Thr-838|

Activated by phosphorylation at Thr-838| inhibited by phosphorylation at Ser-966 and Ser-1033

Multiple alternatively spliced variants of this gene

Involved in membrane recycling

It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system

E2F-5 Polyclonal Antibody, 100ul Pathway and Network Analysis Activated by phosphorylation at Thr-838|The E2F transcription factor 5 encoded by E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a