Synphilin-1 Polyclonal Antibody, 50ul Rotator dissociation of the TFEB/14-3-3 complex

dissociation of the TFEB/14-3-3 complex

An important paralog of this gene is ANO5

Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13

Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD)

Synphilin-1 Polyclonal Antibody, 50ul Rotator dissociation of the TFEB/14-3-3 complexSNCAIP encodes Synphilin 1 containing several protein protein interaction domains, including ankyrin like repeats, a coiled coil domain, and an ATP GTP binding motif. The synphilin 1 interacts with alpha synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants.