RPGR1 Rabbit Polyclonal Antibody, 100ul Antibodies The encoded protein also enhances

The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors

The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway)

It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation

Isoform 2 is a more general and stronger transcriptional coactivator

RPGR1 Rabbit Polyclonal Antibody, 100ul Antibodies The encoded protein also enhancesThis gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness.