POSTN Polyclonal Antibody, 100ul Pipette Micro Tips PubMed: 18235502

PubMed: 18235502

Through the interaction with ILK

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

It may also play a role in cell survival by suppressing apoptosis

POSTN Polyclonal Antibody, 100ul Pipette Micro Tips PubMed: 18235502This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects.