CBLB Polyclonal Antibody, 50ul Glassware Sets Expressed in the kidney only

Expressed in the kidney only in podocytes

characterized by severe proteinuria and loss of the slit diaphragm and foot processes

The encoded preproprotein is cleaved to produce both heavy and light chains

There are multiple isoforms of each of these proteins| either encoded by different genes or the result of alternative splicing of transcripts

CBLB Polyclonal Antibody, 50ul Glassware Sets Expressed in the kidney onlyThe N terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four helix bundle (4H), a calcium binding EF hand and a divergent SH2 domain.,The RING type zinc finger domain mediates binding to an E2 ubiquitin conjugating enzyme.,The UBA domain interacts with poly