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MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Mutations in this gene are

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MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Mutations in this gene arealternative products: Additional isoforms seem to exist Catalytic activity: Cleaves aggrecan at the 360 Ser Phe 361 site. cofactor: Binds 1 zinc ion per subunit. cofactor: Calcium. disease: May play a role in pathological processes participating in rheumatoid arthritis (RA) associated joint tissue destruction. Autoantigen anti MMP19 are frequent in RA patients. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion

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Description

Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment

In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

Its sterilization guarantees safety and efficiency in any experiment

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Mutations in this gene arealternative products: Additional isoforms seem to exist Catalytic activity: Cleaves aggrecan at the 360 Ser Phe 361 site. cofactor: Binds 1 zinc ion per subunit. cofactor: Calcium. disease: May play a role in pathological processes participating in rheumatoid arthritis (RA) associated joint tissue destruction. Autoantigen anti MMP19 are frequent in RA patients. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion

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