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Chk2(Phospho Ser516) Polyclonal Antibody, 50ul Lysosome octamer-binding)

SKU: 47294788735

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Chk2(Phospho Ser516) Polyclonal Antibody, 50ul Lysosome octamer-binding)In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the

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Description

octamer-binding)

TPO-R deficient mice were severely thrombocytopenic

that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin

High levels of expression of this gene enhance the growth of many tumors

Chk2(Phospho Ser516) Polyclonal Antibody, 50ul Lysosome octamer-binding)In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the

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