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p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer It is expressed at high

SKU: 4651300787

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SEK111.00 SEK138.00

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p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer It is expressed at highThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors

Disruption of RFC2 is associated with Williams syndrome

Among its related pathways are Golgi-to-ER retrograde transport and Factors involved in megakaryocyte development and platelet production

GO annotations related to this gene include oxidoreductase activity and cytochrome-b5 reductase activity

p53(Phospho Ser46) Polyclonal Antibody, 20ul Microplate Mixer It is expressed at highThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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