Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing Sequence-specific DNA-binding factor that binds

Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity)

Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19

Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease

An important paralog of this gene is OLFM1

Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing Sequence-specific DNA-binding factor that bindsThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,