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INT7 Rabbit Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Defects in this gene are

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INT7 Rabbit Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Defects in this gene areThis gene encodes a subunit of the integrator complex. The integrator complex associates with the C terminal domain of RNA polymerase II and mediates 3' end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

It is also found to be expressed in lipogenic breast cancers| which suggests a role in controlling tumor lipid metabolism

This protein causes differentiation of brain cells

The protein encoded by this gene binds to calmodulin and is expressed in the centrosome

INT7 Rabbit Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Defects in this gene areThis gene encodes a subunit of the integrator complex. The integrator complex associates with the C terminal domain of RNA polymerase II and mediates 3' end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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