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UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller The gene encoding CLIP4 maps

SKU: 46323796988

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SEK97.20 SEK119.20

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UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller The gene encoding CLIP4 mapsThis gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL E3 ligase complex this enzyme deubiquitinates hypoxia inducible factor (HIF) 1 alpha and thereby causes increased expression of HIF 1alpha targeted genes which play a role in angiogenesis glucose metabolism cell proliferation and

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Description

The gene encoding CLIP4 maps to human chromosome 2p23

Three alternatively spliced transcript variants that encode different protein isoforms have been described

This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells

while the conical bottom ensures optimal sample recovery

UBP20 Rabbit Polyclonal Antibody, 20ul Pipette Controller The gene encoding CLIP4 mapsThis gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL E3 ligase complex this enzyme deubiquitinates hypoxia inducible factor (HIF) 1 alpha and thereby causes increased expression of HIF 1alpha targeted genes which play a role in angiogenesis glucose metabolism cell proliferation and

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