PHACTR4 Polyclonal Antibody, 20ul Reservoirs The encoded preproprotein is secreted

The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer

have been reported to be involved in chromosomal translocations in T-cell leukemia

Mutations in DOK7 are a cause of familial limb-girdle myasthenia autosomal recessive

An important paralog of this gene is TLDC2

PHACTR4 Polyclonal Antibody, 20ul Reservoirs The encoded preproprotein is secretedPHACTR4 (phosphatase and actin regulator 4) encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of PHACTR4 in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for PHACTR4.