BIG2 Polyclonal Antibody, 100ul Purification The cytoplasmic domains of integrins

The cytoplasmic domains of integrins are essential for cell adhesion

chromosome 2 encodes over 1

ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| and White)

The predicted 727-amino acid human protein contains a 29-amino acid presequence

BIG2 Polyclonal Antibody, 100ul Purification The cytoplasmic domains of integrinsADP ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein (ADP ribosylation factor guanine nucleotide exchange factor 2) encoded by ARFGEF2 is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine nucleotide exchange activity and also brefeldin A inhibition.