HXB7 Polyclonal Antibody, 50ul 3D Cell Culture Consumables Secreted phosphoprotein 1 encoded by

Secreted phosphoprotein 1 encoded by SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix

and metastatis

The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes

This gene uses alternative transcription start sites

HXB7 Polyclonal Antibody, 50ul 3D Cell Culture Consumables Secreted phosphoprotein 1 encoded byThis gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.