Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies Crohn's disease and inflammatory bowel

Crohn's disease and inflammatory bowel disease

Multiple alternatively spliced variants| encoding the same protein| have been identified

TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity

Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4

Endothelin B Receptor Polyclonal Antibody, 50ul Primary Antibodies Crohn's disease and inflammatory bowelThe protein encoded by this gene is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple