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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis but studies of other populations

SKU: 45561258617

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PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis but studies of other populationsThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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Description

but studies of other populations have not been able to replicate this association

RAD51 encoded by RAD51(RAD51 recombinase) is a member of the RAD51 protein family

while defects in this gene are associated with multiple types of cancer

EF-hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes

PDX-1 Polyclonal Antibody, 50ul Site-directed Mutagenesis but studies of other populationsThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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